Subclinical phenotypes of asthma

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Subclinical phenotypes of asthma.

PURPOSE OF REVIEW Asthma is a heterogeneous disease. Identification of specific subphenotypes of asthma may further our understanding of pathophysiology and treatment response, leading to the better targeting of both existing and novel antiasthma therapies. An accurate and comprehensive clinicopathological classification system therefore remains an important priority for asthma research. The pr...

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Asthma phenotypes

Currently, categorization based on cluster analysis by objectively grasping the diversity of pathology is being conducted and the diversity of asthma is being categorized as phenotypes. Clinically, there is categorization based on aging and on allergic diathesis which is clinically useful; however, it has not, up to now, come to the point of selection based on phenotype. Subsequently, what is d...

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Clinical phenotypes of asthma.

PURPOSE OF REVIEW Asthma is a phenotypically heterogeneous disorder and, over the years, many different clinical subtypes of asthma have been described. A precise definition of asthma phenotypes is now becoming more and more important, not only for a better understanding of pathophysiologic mechanisms, but in particular to ascertain the specific genes associated with these phenotypes. RECENT ...

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PhenotyPes in AsthmA

Asthma is a heterogeneous disorder presenting with many phenotypes. Improved phenotypic characterization is necessary for linkage of specific genotypes with clinical disease manifestations. Since genotypic and phenotypic heterogeneity are inherent in asthma, patients presenting with different asthma phenotypes may need tailored therapies. The advent of targeted therapies for asthma and clinical...

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Clinical phenotypes of severe asthma.

OBJECTIVE To characterize clinical phenotypes of severe asthma. METHODS A total of 111 patients were retrospectively evaluated at a specialized outpatient clinic. A systematic protocol for patient evaluation and follow-up was applied. Treatment compliance and control of the disease at the end of follow-up were defined by clinical and functional data. Patients who did not meet asthma control c...

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ژورنال

عنوان ژورنال: Current Opinion in Allergy & Clinical Immunology

سال: 2010

ISSN: 1528-4050

DOI: 10.1097/aci.0b013e32833489a9